Mitch Garver hit a two-run home run in the third inning, and Nelson Cruz and C.J. Cron added solo shots to lead the Minnesota Twins to a 6-3 victory over the Detroit Tigers on Friday night in Detroit.

The Twins improved to 42-20 and hold a 10 ½ game lead on Cleveland in the American League Central Division, the largest lead in either league.

Marwin Gonzalez went 4-for-5 to lead Minnesota’s 14-hit attack. Garver went 3-for-5, and Jorge Polanco and Cron added two hits apiece in support of winning pitcher Ryne Harper, who pitched one inning in relief.

Rays 5, Red Sox 1 — At Boston: Yonny Chirinos pitched two-hit ball for eight scoreless innings and Tampa Bay stopped Boston’s four-game winning streak.

Indians 5, Yankees 2 — At Cleveland: Carlos Santana’s two-run homer in the sixth inning helped rookie Zach Plesac get his first major league win and sent Cleveland past New York.

NATIONAL LEAGUE

Phillies 4, Reds 2 — At Philadelphia: Jay Bruce hit a two-run homer, and Zach Eflin threw 6 1/3 sharp innings for Philadelphia. Bruce already has four homers in four games with the NL East-leading Phillies after hitting 14 for Seattle before he was acquired in a trade last week.

Braves 7, Marlins 1 — At Miami: Ronald Acuna Jr. hit a score-settling homer off Jose Urena and Atlanta rode starter Mike Soroka to a win over Miami.

Rockies 5, Mets 1 — At New York: Ian Desmond got plunked in the back by a pitch from New York rookie Drew Gagnon immediately after two colossal Colorado homers, leading to a bench-clearing scrum late in the Rockies’ victory. The bullpens emptied and players from both sides milled together during two separate dustups, but there did not appear to be any serious pushing or shoving and no punches were thrown.

INTERLEAGUE

Diamondbacks 8, Blue Jays 2 — At Toronto: Kevin Cron hit his first major league home run, and David Peralta had a solo shot among his three hits for Arizona. Merrill Kelly (6-6) allowed one run and three hits in seven innings.

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